The Application of Next Generation Sequencing in Forensic DNA Database

Zhao Zhao; Wang Le; Li Sheng; Wang Tong; Liu Bing

doi:doi:10.11648/j.sd.20170504.13

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The Application of Next Generation Sequencing in Forensic DNA Database

Zhao Zhao, Wang Le, Li Sheng, Wang Tong, Liu Bing

Published in Science Discovery (Volume 5, Issue 4)

Received: 19 May 2017 Published: 20 May 2017

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Abstract

With the developing of standardized forensic DNA profiling and information technology, the forensic DNA database has achieved a big success. By managing、searching and sharing through DNA database, the molecular biology and genetics play a crucial role in individual identification, in the meantime, the DNA database also promote the developing of large-scale forensic DNA testing. In recent years, the arising of second generation sequencing(SGS) has substantially changed the way of genetics research, and varies of platform、kit and system has been developed continuously, many of which has been applied in forensic laboratories. So for,the China National DNA Database has expanded to be the largest one in the world, therefore, the SGS needs to incorporated with the DNA database rather than instead of it. So, the compatibility of SGS-based data with massive PCR-CE data in the database is now becoming a critical problem.in this article, the China National DNA Database is introduced, the advantages of SGS and its possible role in the forensic DNA profiling and databasing are elaborated, and the consistency in data storage and the compatibility in comparing of the SGS-based data within the present DNA database are also discussed.

Published in	Science Discovery (Volume 5, Issue 4)
DOI	10.11648/j.sd.20170504.13
Page(s)	257-261
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Forensic DNA Profiling, DNA Database, Second Generation Sequencing, Data Compatibility

References

[1]	Cantor C R and Lim H A. Electrophoresis, Supercomputing and the Humangenomes [M]. Investigative Genetics, 2013, 4: 22.
[2]	张晓东，张传富等。生物信息学数据库研究进展［Ｊ］．生物信息学，2006年，4（3）：143-145。
[3]	孙磊，胡学龙等。生物医学大数据处理的云计算解决方案［Ｊ］．电子测量与仪器学报，2014年，28（11）：1190-1197。
[4]	张晓辉，高晓玲。基于生物信息学数据库的研究与应用［Ｊ］．中国科技信息，2010年，22：44-45。
[5]	姜先华。中国DNA数据库建设应用技术现状及发展趋势［Ｊ］．中国法医学杂志，2011年，26（5）：383-386。
[6]	Richard Hindmarsh,Barbara Prainsack.Global Governance of Forensic DNA Profiling and Databasing[M]. UK,2010:1-11.
[7]	刘冰．现阶段我国DNA数据库发展的几个关键问题［Ｊ］．刑事技术，2015年，40（4）：318-323。
[8]	葛建业，严江伟等．关于法庭科学DNA数据库若干问题的探讨［Ｊ］．中国法医学杂志，2011，26(3):252-255。
[9]	焦文慧，宋辉．英美国家犯罪DNA数据库建设及应用［Ｊ］．上海公安高等专科学校学报，2013，23（2）：86-91。
[10]	胡兰，陈松，张国臣．国家法庭科学DNA数据库建设势在必行［J］．刑事技术，2003(6):3-5。
[11]	焦章平，唐晖，刘雅诚等．建立法医DNA 数据库的初步探讨［J］．中国法医学杂志，2003,18(1):58-59。
[12]	侯一平，王保捷，丛斌，等．中国法医学会物证专业委员会法医 DNA 分析的若干建议[J］．中国法医学杂志，2006,21(5):257-259。
[13]	王乐，叶健，白雪等。二代测序技术及其在法医遗传学中的应用，刑事技术，2015，40(5):353-358。
[14]	Lutz Roewer. DNA fingerprinting in forensics: past, present, future [J]. Investigative Genetics, 2013,4:22.
[15]	Van Neste C, Van Nieuwerburgh F, Van Hoofstat D, et al. Forensic STR analysis using massive parallel sequencing [J]. Forensic Sci Int Genet, 2012, 6: 810: 818.
[16]	Bornman DM, Hester ME,Schuetter JM, et al Short-read, high-throughput sequencing technology for STR genotyping [J]. Biotech Rapid Dispatches, 2012: 1-6.
[17]	Fordyce SL, Mogensen HS, Borsting C, et al. Second-generation sequencing of forensic STRs using the ion torrent HID STR 10-plex and the Ion PGM [J]. Forensic Sci Int Genet, 2015, 14: 132-140.
[18]	Scheible M,Loreile O, et al. Short tandem repeat typing on the 454 platform:strategies and considerations for targeted sequencing of common forensic markers [J]. Forensic Sci Int Genet, 2014, 12: 107-119.
[19]	Sarah L.Fordyce, Helle Smidt, et al. Second-generation sequencing of forensic STRs using the Ion Torrent TM HID STR 10-plex and the Ion PGM TM [J]. Forensic Sci Int Genet, 2015, 14: 132-140.

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APA Style

Zhao Zhao, Wang Le, Li Sheng, Wang Tong, Liu Bing. (2017). The Application of Next Generation Sequencing in Forensic DNA Database. Science Discovery, 5(4), 257-261. https://doi.org/10.11648/j.sd.20170504.13

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ACS Style

Zhao Zhao; Wang Le; Li Sheng; Wang Tong; Liu Bing. The Application of Next Generation Sequencing in Forensic DNA Database. Sci. Discov. 2017, 5(4), 257-261. doi: 10.11648/j.sd.20170504.13

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AMA Style

Zhao Zhao, Wang Le, Li Sheng, Wang Tong, Liu Bing. The Application of Next Generation Sequencing in Forensic DNA Database. Sci Discov. 2017;5(4):257-261. doi: 10.11648/j.sd.20170504.13

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@article{10.11648/j.sd.20170504.13,
  author = {Zhao Zhao and Wang Le and Li Sheng and Wang Tong and Liu Bing},
  title = {The Application of Next Generation Sequencing in Forensic DNA Database},
  journal = {Science Discovery},
  volume = {5},
  number = {4},
  pages = {257-261},
  doi = {10.11648/j.sd.20170504.13},
  url = {https://doi.org/10.11648/j.sd.20170504.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sd.20170504.13},
  abstract = {With the developing of standardized forensic DNA profiling and information technology, the forensic DNA database has achieved a big success. By managing、searching and sharing through DNA database, the molecular biology and genetics play a crucial role in individual identification, in the meantime, the DNA database also promote the developing of large-scale forensic DNA testing. In recent years, the arising of second generation sequencing(SGS) has substantially changed the way of genetics research, and varies of platform、kit and system has been developed continuously, many of which has been applied in forensic laboratories. So for,the China National DNA Database has expanded to be the largest one in the world, therefore, the SGS needs to incorporated with the DNA database rather than instead of it. So, the compatibility of SGS-based data with massive PCR-CE data in the database is now becoming a critical problem.in this article, the China National DNA Database is introduced, the advantages of SGS and its possible role in the forensic DNA profiling and databasing are elaborated, and the consistency in data storage and the compatibility in comparing of the SGS-based data within the present DNA database are also discussed.},
 year = {2017}
}

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TY  - JOUR
T1  - The Application of Next Generation Sequencing in Forensic DNA Database
AU  - Zhao Zhao
AU  - Wang Le
AU  - Li Sheng
AU  - Wang Tong
AU  - Liu Bing
Y1  - 2017/05/20
PY  - 2017
N1  - https://doi.org/10.11648/j.sd.20170504.13
DO  - 10.11648/j.sd.20170504.13
T2  - Science Discovery
JF  - Science Discovery
JO  - Science Discovery
SP  - 257
EP  - 261
PB  - Science Publishing Group
SN  - 2331-0650
UR  - https://doi.org/10.11648/j.sd.20170504.13
AB  - With the developing of standardized forensic DNA profiling and information technology, the forensic DNA database has achieved a big success. By managing、searching and sharing through DNA database, the molecular biology and genetics play a crucial role in individual identification, in the meantime, the DNA database also promote the developing of large-scale forensic DNA testing. In recent years, the arising of second generation sequencing(SGS) has substantially changed the way of genetics research, and varies of platform、kit and system has been developed continuously, many of which has been applied in forensic laboratories. So for,the China National DNA Database has expanded to be the largest one in the world, therefore, the SGS needs to incorporated with the DNA database rather than instead of it. So, the compatibility of SGS-based data with massive PCR-CE data in the database is now becoming a critical problem.in this article, the China National DNA Database is introduced, the advantages of SGS and its possible role in the forensic DNA profiling and databasing are elaborated, and the consistency in data storage and the compatibility in comparing of the SGS-based data within the present DNA database are also discussed.
VL  - 5
IS  - 4
ER  -

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Author Information

Zhao Zhao

Institute of Forensic Science of Ministry of Public Security, Beijing, China
Wang Le

Institute of Forensic Science of Ministry of Public Security, Beijing, China
Li Sheng

Institute of Forensic Science of Ministry of Public Security, Beijing, China
Wang Tong

Institute of Forensic Science of Ministry of Public Security, Beijing, China
Liu Bing

Institute of Forensic Science of Ministry of Public Security, Beijing, China

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Plain Text BibTeX RIS

APA Style

Zhao Zhao, Wang Le, Li Sheng, Wang Tong, Liu Bing. (2017). The Application of Next Generation Sequencing in Forensic DNA Database. Science Discovery, 5(4), 257-261. https://doi.org/10.11648/j.sd.20170504.13

Copy | Download

ACS Style

Zhao Zhao; Wang Le; Li Sheng; Wang Tong; Liu Bing. The Application of Next Generation Sequencing in Forensic DNA Database. Sci. Discov. 2017, 5(4), 257-261. doi: 10.11648/j.sd.20170504.13

Copy | Download

AMA Style

Zhao Zhao, Wang Le, Li Sheng, Wang Tong, Liu Bing. The Application of Next Generation Sequencing in Forensic DNA Database. Sci Discov. 2017;5(4):257-261. doi: 10.11648/j.sd.20170504.13

Copy | Download

@article{10.11648/j.sd.20170504.13,
  author = {Zhao Zhao and Wang Le and Li Sheng and Wang Tong and Liu Bing},
  title = {The Application of Next Generation Sequencing in Forensic DNA Database},
  journal = {Science Discovery},
  volume = {5},
  number = {4},
  pages = {257-261},
  doi = {10.11648/j.sd.20170504.13},
  url = {https://doi.org/10.11648/j.sd.20170504.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sd.20170504.13},
  abstract = {With the developing of standardized forensic DNA profiling and information technology, the forensic DNA database has achieved a big success. By managing、searching and sharing through DNA database, the molecular biology and genetics play a crucial role in individual identification, in the meantime, the DNA database also promote the developing of large-scale forensic DNA testing. In recent years, the arising of second generation sequencing(SGS) has substantially changed the way of genetics research, and varies of platform、kit and system has been developed continuously, many of which has been applied in forensic laboratories. So for,the China National DNA Database has expanded to be the largest one in the world, therefore, the SGS needs to incorporated with the DNA database rather than instead of it. So, the compatibility of SGS-based data with massive PCR-CE data in the database is now becoming a critical problem.in this article, the China National DNA Database is introduced, the advantages of SGS and its possible role in the forensic DNA profiling and databasing are elaborated, and the consistency in data storage and the compatibility in comparing of the SGS-based data within the present DNA database are also discussed.},
 year = {2017}
}

Copy | Download

TY  - JOUR
T1  - The Application of Next Generation Sequencing in Forensic DNA Database
AU  - Zhao Zhao
AU  - Wang Le
AU  - Li Sheng
AU  - Wang Tong
AU  - Liu Bing
Y1  - 2017/05/20
PY  - 2017
N1  - https://doi.org/10.11648/j.sd.20170504.13
DO  - 10.11648/j.sd.20170504.13
T2  - Science Discovery
JF  - Science Discovery
JO  - Science Discovery
SP  - 257
EP  - 261
PB  - Science Publishing Group
SN  - 2331-0650
UR  - https://doi.org/10.11648/j.sd.20170504.13
AB  - With the developing of standardized forensic DNA profiling and information technology, the forensic DNA database has achieved a big success. By managing、searching and sharing through DNA database, the molecular biology and genetics play a crucial role in individual identification, in the meantime, the DNA database also promote the developing of large-scale forensic DNA testing. In recent years, the arising of second generation sequencing(SGS) has substantially changed the way of genetics research, and varies of platform、kit and system has been developed continuously, many of which has been applied in forensic laboratories. So for,the China National DNA Database has expanded to be the largest one in the world, therefore, the SGS needs to incorporated with the DNA database rather than instead of it. So, the compatibility of SGS-based data with massive PCR-CE data in the database is now becoming a critical problem.in this article, the China National DNA Database is introduced, the advantages of SGS and its possible role in the forensic DNA profiling and databasing are elaborated, and the consistency in data storage and the compatibility in comparing of the SGS-based data within the present DNA database are also discussed.
VL  - 5
IS  - 4
ER  -

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